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Growth factors: regulation of normal and neoplastic growth
L Pusztai1, C E Lewis, J Lorenzen
1University of Oxford, Nuffield Department of Pathology and Bacteriology, John Radcliffe Hospital, U.K.
The Journal of Pathology
|February 1, 1993
Abstract:
This paper presents an overview of current trends in growth factor research. The first part of the review considers the current classification of growth factors and their receptors. A model of cell proliferation regulation by growth factors is then presented. The final section reviews the latest concepts of the involvement of growth factors in the development of neoplasia.