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Acute renal failure in theophylline poisoning
1Department of Internal Medicine, Catharina Hospital, Eindhoven, Netherlands.
The Netherlands Journal of Medicine
|February 1, 1993
Abstract:
A 57-yr-old woman with an intentional theophylline overdose complicated by rhabdomyolysis, renal failure and microangiopathic haemolytic anaemia is reported. Severe renal vasoconstriction, myoglobinuria and antagonism of adenosine are considered to be the principal pathophysiological renal mechanisms involved.