Polyautoimmunity in a young woman

¹Department of Rheumatology, Edith Cavell Hospital, Bretton Gate, Peterborough.

|March 1, 1993

Abstract:

A young woman with the HLA phenotype A1, A2, B5, B8, DR3, DR4 developed RA, idiopathic thrombocytopenic purpura (ITP), pernicious anaemia (PA), Hashimoto's thyroiditis (HT), systemic sclerosis (SS), pancreatic exocrine insufficiency (PEI) and coeliac disease (CD) before dying from vasculitic complications. A family study revealed RA, PA and insulin-dependent diabetes mellitus (IDDM) amongst her first degree relatives. Her case emphasizes the clinical and immunogenetic links between the autoimmune diseases.

Related Concept Videos

Articles linked to this work by shared authors, journal, and citation graph.

Related Experiment Videos

Polyautoimmunity in a young woman

Related Concept Videos

Magnetic resonance imaging for low back pain: indications and limitations.

Magnetic resonance imaging for low back pain: indications and limitations.

Dysphagia and other manifestations of oesophageal involvement in the musculoskeletal diseases.

Arthritis artefacta: factitious disease in rheumatology.

Rheumatoid blood decreases the adherence of polymorphonuclear cells (PMNs) to cultured endothelium.

Adherence of rheumatoid polymorphonuclear cells (PMNs) to cultured endothelial cell monolayers.

Hypothyroid myopathy as a complication of interferon alpha therapy for chronic hepatitis C virus infection.

Benefit of 6 months long-term physical training in polymyositis/dermatomyositis patients.

Circulating interleukin-16 in systemic lupus erythematosus.

Antibodies to Klebsiella pneumoniae lipopolysaccharide in patients with ankylosing spondylitis.

Clinical course and remission rate in patients with early rheumatoid arthritis: relationship to outcome after 5 years.

A study of the frequency of pericardial and pleural effusions in scleroderma.

Comparing the efficacy of first-line immunotherapies in autoimmune encephalitis: a scoping review.

Herbal hot compress combined with bianstone warm ironing improves anxiety and cognitive impairment via gut-brain-HPA axis in pubertal mesenteric lymphadenitis rats.

Elevated ALT correlates with severe liver injury, monocyte infiltration, and Pro-inflammatory immune dysregulation in chronic hepatitis B virus infection.

Immunological dysregulation of follicular helper T cells, follicular regulatory T cells, and follicular cytotoxic T cells is associated with disease activity and identifies exploratory immune patterns in rheumatoid arthritis.

Cryo-EM reveals patient- versus organ-specific structural diversity and bound ligands in λ6 light chain amyloids.

Diagnostic performance of antibodies against extractable nuclear antigens detected by immunoblot in the differentiation of connective tissue diseases.

Related Experiment Videos

Polyautoimmunity in a young woman

Abstract:

Related Concept Videos

Related Articles