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A case of collagenofibrotic glomerulopathy associated with hepatic perisinusoidal fibrosis
S Mizuiri1, A Hasegawa, A Kikuchi
1Department of Nephrology, Toho University School of Medicine, Tokyo, Japan.
Nephron
|January 1, 1993
Abstract:
A patient with collagenofibrotic glomerulopathy associated with hepatic persinusoidal fibrosis is described. Renal biopsy revealed that the glomerular tufts contained homogeneous material that was proved by electron microscopy to be collagen fibers. The material was reactive to anti-type III collagen monoclonal antibody. Liver biopsy also showed an increase of type III collagen fibers in the perisinusoidal area. Since the serum procollagen III peptide level was elevated in this patient, fibrosis may have been simultaneously activated in kidney and liver by some unknown condition.