Related Experiment Video
Updated: Aug 12, 2026

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects
Published on: April 11, 2012
The four biomechanical stages of fracture repair
Abstract:
Based on analysis of the torque-angle curves and roentgenographic findings in fifty-three healing tibial fractures in rabbits tested in torsion to failure, four biomechanical stages of fracture healing were defined, as follows: Stage I--failure through original fracture site, with low stiffness; Stage II--failure through original fracture site, with high stiffness; Stage III--failure partially through original fracture site and partially through intact bone, with high stiffness; and Stage IV--failure entirely through intact bone, with high stiffness. These stages correlated with the progressive increases in the average torque and energy absorption to failure as healing progressed and also with the average times since the original experimental fracture. It is hoped that this system of staging will provide both a standard by which important variables related to ultimate strength of healing fractures can be correlated and an objective way to predict delayed unions and non-unions and to determine the level of activity that is safe for patients with a healing fracture.
Related Concept Videos
Bone Remodeling
Growth of Cartilage and Bone Tissue
Overview of Regeneration and Repair
Regeneration
All animals have varying degrees of...
Phases of Wound Repair
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Bone Remodeling and Repair

