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Autoantibodies to nuclear mitotic apparatus in a patient with vitiligo and autoimmune thyroiditis
1Department of Dermatology, University of Graz, Austria.
Dermatology (Basel, Switzerland)
|January 1, 1993
Abstract:
Circulating autoantibodies against the nuclear mitotic apparatus (NuMA) protein have been detected in sera of patients with a variety of connective tissue diseases. A close relation of anti-NuMA antibodies to define subsets of these diseases could not be established. This is the first description of a patient with vitiligo, autoimmune thyroiditis and a high titer of antibodies against NuMA on Hep-2 cells. The possibility of a beginning of multiple autoimmune syndrome cannot be excluded.