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Published on: January 14, 2014
1;19 translocation in human meningioma
T Prempree1, R Amornmarn, W J Faillace
1University of Florida, Health Science Center, Jacksonville 32209.
Cancer
|April 1, 1993
Summary
This study reports a unique case of meningioma with a sole chromosome 1;19 translocation, unlike the typical chromosome 22 loss. Further research is needed to understand its role in meningioma genesis.
Area of Science:
- Cytogenetics
- Oncology
- Neurosurgery
Background:
- Meningiomas frequently exhibit chromosome 22 loss (70%), with 30% showing normal karyotypes.
- Structural chromosomal changes are rare and often coexist with chromosome losses in meningiomas.

