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Related Experiment Videos

EOP and Dk/L: the quest for hyper transmissibility

W J Benjamin1

  • 1University of Alabama, Birmingham School of Optometry 35294.

Journal of the American Optometric Association
|March 1, 1993
PubMed
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Higher oxygen transmissibility (Dk/L) in contact lenses leads to increased oxygen supply to the eye, approaching a limit. New classifications for oxygen permeability and transmissibility are proposed for better contact lens fitting and design.

Area of Science:

  • Ophthalmology
  • Biomaterials Science
  • Optometry

Background:

  • Corneal oxygenation is crucial for eye health, influenced by contact lens oxygen transmissibility (Dk/L).
  • Existing classifications for contact lens oxygen properties may not fully capture their physiological impact.

Purpose of the Study:

  • To investigate the relationship between human equivalent oxygen percentage (human EOP) and Dk/L for various contact lenses.
  • To establish standardized classifications for oxygen transmissibility and permeability based on EOP.

Main Methods:

  • Examined 28 contact lenses with Dk/L ranging from 14.2 to 134.4 using a gas-to-gas method.
  • Correlated human EOP with Dk/L using semi-logarithmic regression analysis.

Main Results:

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  • A positive correlation was found between human EOP and Dk/L, with EOP approaching a plateau around 20% as Dk/L increased.
  • The semi-logarithmic model showed a high linear correlation (R2 = 0.95) but had limitations at extreme values.
  • Defined new ranges for contact lens oxygen transmissibility (low, medium, high, super, hyper).

Conclusions:

  • Rigid gas permeable lenses with high Dk/L offer improved corneal oxygenation, potentially allowing for more complex optical corrections.
  • Advancements in hyper-permeable materials could lead to contact lenses where corneal oxygenation is minimally affected by lens design variations.