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[Microbiological determination of netilmicin using a thin-layer chromatography scanner]

Y Tsuda¹, H Wakamatsu, E Yoshizawa

¹Research Laboratory, Schering-Plough Kabushiki Kaisha.

The Japanese Journal of Antibiotics

|January 1, 1993

Summary

This study introduces a novel colorimetric bioassay for netilmicin (NTL), an aminoglycoside antibiotic. The method utilizes Bacillus subtilis to produce carbon dioxide, causing a color change in thymolphthalein for NTL detection.

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Area of Science:

Analytical Chemistry
Microbiology
Biotechnology