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Autonomic nervous system function

P A Low1

  • 1Department of Neurology, Mayo Clinic, Rochester, MN 55905.

Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society
|January 1, 1993
PubMed
Summary
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Clinical autonomic neurophysiology tests should be noninvasive and relevant. This study details essential tests for diagnosing autonomic disorders like generalized autonomic failure and postural orthostatic tachycardia syndrome.

Area of Science:

  • Clinical Neurophysiology
  • Autonomic Nervous System Function

Background:

  • Clinical autonomic neurophysiology requires tests that are noninvasive, sensitive, specific, reproducible, relevant, and efficient.
  • Laboratory evaluation is crucial for suspected generalized autonomic failure, mimic disorders, small-fiber neuropathy, autonomic neuropathies, sympathetically maintained pain, and postural orthostatic tachycardia syndrome.

Purpose of the Study:

  • To outline the essential criteria for autonomic function tests.
  • To describe recommended test batteries for clinical autonomic neurophysiology laboratories.
  • To highlight the importance of subject preparation and comprehensive autonomic system evaluation.

Main Methods:

  • The Mayo laboratory employs two primary test batteries: the autonomic reflex screen and the reflex sympathetic dystrophy (RSD) screen.

Related Experiment Videos

  • The autonomic reflex screen includes quantitative sudomotor axon reflex test (QSART), orthostatic blood pressure (BP) and heart rate (HR) responses to tilt, HR response to deep breathing, Valsalva ratio, and beat-to-beat BP responses.
  • The RSD screen involves recording skin temperature, resting sweat output, and bilateral QSART distributions.

    • Main Results:

    • The described tests provide a comprehensive evaluation of autonomic nervous system function.
    • The methodologies ensure sensitivity, specificity, and reproducibility for accurate diagnosis.
    • Subject preparation is emphasized as critical for reliable test outcomes.

    Conclusions:

    • The presented test batteries are suitable for clinical autonomic neurophysiology laboratories.
    • These evaluations aid in diagnosing a range of autonomic disorders.
    • The approach ensures physiologically and clinically relevant data for patient care.