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Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
Published on: May 31, 2016
The challenge of calcific aortitis
1Department of Surgery, Tampa General Hospital, Florida.
Insights
Elderly patients with calcified aortas pose surgical challenges. A new cannula introducer technique improved cannulation success, reducing risks in complex cardiac surgeries.
Area of Science:
- Cardiovascular Surgery
- Geriatric Medicine
- Vascular Biology
Background:
- Increasing prevalence of cardiovascular procedures in the elderly population.
- Ascending aortic calcification presents significant challenges for aortic cannulation.
- Elevated postoperative stroke and mortality rates associated with aortic calcification.
Observation:
- Traditional cannulation methods are difficult and risky in patients with severe aortic calcification.
- Calcific debris embolization is a suspected cause of neurological and cardiac complications.
- A novel cannula introducer was utilized to facilitate cannulation in challenging cases.
Findings:
- The cannula introducer enabled successful aortic cannulation in 19 high-risk patients (average age 73.7).
- Various cardiac arrest and aortic cross-clamping techniques were employed.
- Sutures were passed internally to prevent plaque displacement and dissection.
Implications:
- This technique offers a viable solution for performing complex cardiac surgeries in elderly patients with severely calcified aortas.
- Minimizing embolic events may reduce postoperative stroke and mortality.
- Further research into optimizing cannulation strategies for calcified aortas is warranted.
Abstract:
Coronary bypass and valvular operations have become more prevalent as the nation's elderly population grew 21% within the last decade. Ascending aortic calcification was a manifestation of this aging process. Aortic cannulation appeared impossible. Postoperatively, the stroke rate reached 14%, and the number of unexpected deaths rose sharply. Embolization of calcific and arteriosclerotic debris to cerebral and coronary vessels is believed to be the cause. The sharp, beveled, and narrowed jet-forming tips assaulted the delicate and soft intima of the artery. Nineteen cases of severely calcified aorta with increased predictable risk factors were operated on within the past 5 years. There were 12 coronary bypass grafts, 4 ventricular aneurysmectomies, and 3 valve replacements. Five of these cases were redo operations. The average age for these patients was 73.7 years. With the availability of the cannula introducer, we were able to find a small soft spot inside the arch or ascending aorta and cannulate these patients. We began to cool the patients down immediately and chose one of the three available methods for cardiac arrest. By changing the angle of application and direction of the axis of the clamp, we could cross-clamp the aorta loosely in 11 patients and administer cardioplegia. Intraluminal balloon occlusion of the ascending aorta was used once. The remainder of the cases had fibrillatory arrest. All proximal anastomoses in the coronary patients were done while on cross-clamp, intraluminal balloon occlusion, or brief periods of circulatory arrest. All sutures were passed from inside the aorta to avoid displacing or dissecting calcified plaques.(ABSTRACT TRUNCATED AT 250 WORDS)
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