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Myocardial functions of children with acute poststreptococcal glomerulonephritis
1Nephrology Department of Pediatrics, Ondokuz Mayis University Medical Faculty, Samsun, Turkey.
Insights
Acute poststreptococcal glomerulonephritis (APSGN) can impair left ventricular function, potentially affecting disease outcomes. Myocardial dysfunction was observed in some patients during acute and convalescent phases, highlighting the need for cardiac monitoring.
Area of Science:
- Cardiology
- Nephrology
- Pediatrics
Background:
- Acute poststreptococcal glomerulonephritis (APSGN) is a common renal disease in children.
- Cardiac involvement in APSGN is not fully understood, particularly concerning left ventricular function.
Purpose of the Study:
- To investigate left ventricular function in patients with APSGN.
- To determine the prevalence and potential impact of myocardial dysfunction in APSGN.
Main Methods:
- Two-dimensional and M-mode echocardiography were used.
- 35 patients with APSGN and 25 healthy controls were studied.
Main Results:
- Six patients (17%) exhibited myocardial dysfunction during acute and convalescent APSGN phases.
- No correlation was found between myocardial dysfunction and hypertension, cardiac failure, or effusions.
- One patient with myocardial dysfunction died.
Conclusions:
- Left ventricular dysfunction can occur during the acute congestive phase of APSGN.
- Impaired left ventricular function may influence the prognosis of APSGN.
Abstract:
Left ventricular function was investigated by two-dimensional and M-mode echocardiography in 35 patients with acute poststreptococcal glomerulonephritis and in 25 healthy controls. Six of these patients were found to have myocardial dysfunction during the acute congestive phase and convalescent phases of APSGN. One of these 6 patients, later, died. No correlations were determined between myocardial dysfunction and hypertension, cardiac failure, pericardial and pleural effusion. As a result, left ventricular function may be impaired in acute congestive phase of APSGN and this may affect the course and prognosis of the disease.