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Cataract: relationship between nutrition and oxidation

A Taylor1

  • 1Laboratory for Nutrition and Vision Research, USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111.

Journal of the American College of Nutrition
|April 1, 1993
PubMed
Summary
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Optimizing antioxidant intake, including vitamins and nutrients from fruits and vegetables, can delay age-related cataract development. This nutritional approach may significantly reduce cataract surgeries and healthcare costs.

Area of Science:

  • Ophthalmology
  • Nutritional Science
  • Gerontology

Background:

  • Cataract, or lens opacification, results from accumulated damaged proteins due to aging and oxidative stress.
  • Proteolytic pathways decline with age, hindering the removal of damaged lens proteins.
  • Cataract surgery is a major healthcare expense, particularly in the United States, costing billions annually.

Purpose of the Study:

  • To review the evidence linking antioxidant intake to delayed cataract development.
  • To explore the potential of nutritional interventions in managing age-related cataracts.
  • To assess the impact of delaying cataract on healthcare costs.

Main Methods:

  • Literature review of studies on antioxidants, nutrition, and cataract.
  • Analysis of data correlating dietary intake of antioxidants (ascorbate, carotenoids, tocopherol) with cataract prevalence.

Related Experiment Videos

  • Examination of the relationship between plasma antioxidant status and vision health.

    • Main Results:

    • Elevated intake of antioxidants, including ascorbate, carotenoids, and tocopherol, is associated with delayed cataract development.
    • Positive associations were observed between plasma antioxidant status, fruit and vegetable consumption, and vision health.
    • Delaying cataract by 10 years could potentially eliminate over half of cataract surgeries and associated costs in the US.

    Conclusions:

    • Optimal antioxidant nutrition can extend lens function and delay cataract formation.
    • Nutritional strategies represent a viable approach to mitigate the burden of age-related cataracts.
    • Improving dietary antioxidant intake may significantly reduce healthcare expenditures related to cataract surgery.