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Identification of 34 apolipoprotein(a) isoforms: differential expression of apolipoprotein(a) alleles between
S M Marcovina1, Z H Zhang, V P Gaur
1Department of Medicine, Northwest Lipid Research Laboratories, University of Washington, Seattle, WA.
Biochemical and Biophysical Research Communications
|March 31, 1993
Abstract:
A total of 34 different apo(a) isoforms was identified in a population sample of 806 American Whites and 701 American Blacks by a high resolution SDS-agarose gel electrophoretic method followed by immunoblotting. Among the 1507 individuals tested, 79% revealed double-banded phenotypes and 21% single-banded phenotypes. The frequencies of the apo(a) isoforms differed between American Blacks and Whites (p < 0.001).