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[Lysozyme activity in cat feces]

S Fischer1, E Müller, W Kraft

  • 1I. Medizinischen Tierklinik, Ludwig-Maximilians-Universität München.

Tierarztliche Praxis
|February 1, 1993
PubMed
Summary
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Fecal lysozyme activity is significantly higher in cats with chronic diarrhea compared to healthy cats. This biomarker aids in assessing treatment and progress for feline chronic diarrhea.

Area of Science:

  • Veterinary Medicine
  • Biochemistry

Context:

  • Chronic diarrhea is a common and complex condition in domestic cats.
  • Fecal lysozyme, an enzyme with antimicrobial properties, has been investigated as a potential biomarker in gastrointestinal diseases.

Purpose:

  • To determine fecal lysozyme activity in healthy cats and cats suffering from chronic diarrhea.
  • To establish reference values for fecal lysozyme and assess its diagnostic utility in feline chronic diarrhea.

Summary:

  • Fecal lysozyme activity was measured in healthy cats (mean 1.3 ± 0.9 µg/g) and cats with chronic diarrhea (mean 3.4 ± 3.3 µg/g).
  • A statistically significant difference was observed between the two groups, with higher activity in diarrheic cats.
  • However, lysozyme activity alone could not differentiate specific underlying diseases causing chronic diarrhea.

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Impact:

  • Fecal lysozyme determination can serve as a valuable screening test for chronic diarrhea in cats.
  • It offers a non-invasive method to monitor treatment effectiveness and disease progression.