Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The intravenously administered glycerol test

S Aso1, H Kimura, S Takeda

  • 1Department of Otolaryngology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan.

Acta Oto-Laryngologica. Supplementum
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intraoperative endoscopic electrohydraulic lithotripsy of pancreatic stones.

International journal of pancreatology : official journal of the International Association of Pancreatology·1992
Same author

[Prevention of hepatitis B in a hospital].

[Nihon koshu eisei zasshi] Japanese journal of public health·1992
Same author

Modification of radiosensitivity by the so-called tissue recovery stimulator. I. Radiosensitizing effects of solcoseryl.

Journal of radiation research·1992
Same author

[Hypoxic ventilatory response and hypoxic depression].

Nihon Kyobu Shikkan Gakkai zasshi·1992
Same author

Impairment of the TSH signal transduction system in human thyroid carcinoma cells.

Experimental cell research·1992
Same author

Role of adrenergic neuronal activity in the yawning induced by tacrine and NIK-247 in rats.

Pharmacology, biochemistry, and behavior·1992

The glycerol dehydration test for Menière's disease was evaluated using oral and intravenous methods. Intravenous administration proved safe and effective, yielding similar diagnostic rates for Menière's disease.

Area of Science:

  • Otolaryngology
  • Neurology
  • Diagnostic Medicine

Background:

  • Menière's disease is a complex inner ear disorder.
  • Accurate diagnostic tests are crucial for effective treatment.
  • The glycerol dehydration test is a known diagnostic tool.

Purpose of the Study:

  • To evaluate three distinct methods for performing the glycerol dehydration test.
  • To assess the safety and efficacy of different glycerol administration routes.
  • To compare diagnostic accuracy for Menière's disease.

Main Methods:

  • Method 1: Oral administration of 50g of 50% glycerol solution.
  • Method 2: Intravenous administration of 500ml of 10% glycerol in saline with 5% fructose.
  • Method 3: Intravenous administration of 200ml of the same glycerol solution.

Related Experiment Videos

Main Results:

  • Intravenous glycerol administration was found to be safe with no reported side effects.
  • Both intravenous methods demonstrated comparable rates of positive diagnosis for Menière's disease.
  • Oral administration method was also evaluated for comparison.

Conclusions:

  • Intravenous administration of glycerol solutions is a safe and viable option for the glycerol dehydration test.
  • The tested intravenous methods show potential for diagnosing Menière's disease.
  • Further research may refine intravenous protocols for optimal diagnostic yield.