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Effects of isosorbide in patients with Menière's disease
K Kanda1, Y Watanabe, H Shojaku
1Department of Otolaryngology, Toyama Medical and Pharmaceutical University, Japan.
Acta Oto-Laryngologica. Supplementum
|January 1, 1993
Abstract:
The effects of isosorbide on vertigo, disability, hearing loss and tinnitus in 32 patients with Menière's disease were evaluated after a 24-month observation period. Vestibular symptoms in 80% of patients were assessed as improved according to the 1985 AAO-HNS post-treatment reporting criteria. In contrast, the effect of this osmotic diuretic on cochlear symptoms was limited.