[Mechanisms of death of free radical states in proteins]

Mechanism of the death of free radicals formed under the effect of different destructing factors in proteins without a prosthetic group is considered. The death of macroradicals in proteins is suggested to be due to a recombination of free radical states of aromatic amino acid residues and atom hydrogen braking away as a result of transformation of the middle radicals -NH-C alpha R-CO- from the nearest NH-group. Possible way of middle radicals transformation is proposed which leads to the breakage of hydrogen. The mechanism of macroradicals death considered explains basic experimental results obtained in this field.