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Related Experiment Videos

Chirality in the umbilical cord

S Fletcher1

  • 1Tawam Hospital, Abu Dhabi, United Arab Emirates.

British Journal of Obstetrics and Gynaecology
|March 1, 1993
PubMed
Summary
This summary is machine-generated.

Left-handed umbilical cord helices are most common, found in over 76% of newborns. This study determined normal proportions of umbilical cord chirality, a key feature for medical records.

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Area of Science:

  • Medical Science
  • Developmental Biology
  • Anatomy

Background:

  • The umbilical cord's vascular helix exhibits chirality, a property with potential clinical significance.
  • Understanding the normal distribution of umbilical cord chirality is essential for accurate medical documentation.

Purpose of the Study:

  • To ascertain the prevalence of different chiral varieties in umbilical cord vascular helices.
  • To establish normative proportions for umbilical cord chirality in a specific population.

Main Methods:

  • Statistical analysis, including chi-squared tests and binomial distribution, was employed to assess sex differences and compare observed frequencies to expected values.
  • The study analyzed umbilical cords from 200 singleton Gulf Arab newborns (100 male, 100 female) from normal births in the United Arab Emirates.

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Main Results:

  • Left-handed helices were predominant (76.5%), followed by right-handed (15.5%).
  • Mixed chiral forms occurred in 6.5% of cases, and 1.5% were indeterminable due to poor helix formation or varices.
  • No significant sex-based difference in chirality was observed.

Conclusions:

  • Umbilical cord chirality is a readily determinable characteristic and a unique feature of the cord.
  • Incorporating chirality data into birth and pathological records may offer valuable insights into fetal and postnatal characteristics and morbidity.