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Updated: Aug 14, 2026

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Expression, Isolation, and Purification of Soluble and Insoluble Biotinylated Proteins for Nerve Tissue Regeneration
Published on: January 22, 2014
Brittle nails: response to daily biotin supplementation
L G Hochman1, R K Scher, M S Meyerson
1Department of Dermatology, College of Physicians and Surgeons of Columbia University, New York, New York.
Cutis
|April 1, 1993
Summary
Biotin supplements may improve brittle nails. A study found 63% of patients taking daily biotin experienced clinical improvement, suggesting it
Area of Science:
- Dermatology
- Nutritional Science
Background:
- Brittle nails are a common condition affecting nail health.
- Biotin, a B-complex vitamin, is often recommended for nail health.
Purpose of the Study:
- To evaluate the effectiveness of biotin supplementation in patients with brittle nails.
Main Methods:
- Retrospective analysis of 44 patients with brittle nails prescribed biotin.
- Subjective evaluation of 35 patients on daily biotin supplementation.
Main Results:
- A 25% increase in nail plate thickness was observed.
- 63% of patients taking daily biotin reported clinical improvement.
- 37% reported no change in their condition.
Conclusions:
- Biotin supplementation shows a positive response in treating brittle nails for some individuals.
- Further research is warranted to confirm these findings.
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