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Achromobacter xylosoxidans keratitis following penetrating keratoplasty
D S Siganos1, I G Tselentis, M E Papatzanaki
1University of Crete-School of Health Sciences, Department of Ophthalmology, Greece.
Background:
Achromobacter xylosoxidans is a bacterium not previously reported in a corneal infection. We present a case of infectious keratitis caused by this organism, occurring 1 month following penetrating keratoplasty.
Methods:
Identification of the organism was accomplished by staining, culture, and sensitivity testing of the corneal scraping obtained from the involved area. The infection responded to subconjunctival ticarcillin, piperacillin eye drops, and I.V. azlocillin.
Results:
Complete healing with a resultant corneal opacity involving mostly the anterior and middle stroma was achieved 1 month later.
Conclusions:
A. xylosoxidans should be considered as a potential pathogen in instances of early postkeratoplasty infectious keratitis.
Insights
Achromobacter xylosoxidans, a bacterium, caused infectious keratitis after a corneal transplant. This early post-keratoplasty infection successfully healed with specific antibiotic treatments.
Area of Science:
- Ophthalmology
- Microbiology
- Infectious Diseases
Background:
- Achromobacter xylosoxidans is identified as a novel pathogen in infectious keratitis.
- This case details an infection occurring one month post-penetrating keratoplasty.
Observation:
- Corneal scraping analysis confirmed the presence of Achromobacter xylosoxidans.
- The infection involved the anterior and middle corneal stroma.
Findings:
- The infectious keratitis demonstrated a positive response to a combination of topical and intravenous antibiotics, including ticarcillin, piperacillin, and azlocillin.
- Complete healing of the cornea was achieved within one month.
Implications:
- Achromobacter xylosoxidans should be recognized as a potential cause of early infectious keratitis following corneal transplantation.
- This finding expands the spectrum of pathogens to consider in post-keratoplasty infections.