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The effect of halothane dose on striatal dopamine: an in vivo microdialysis study
K Miyano1, Y Tanifuji, E I Eger
1Department of Anesthesiology, Jikei University School of Medicine, Tokyo, Japan.
Brain Research
|March 12, 1993
Abstract:
The relationship between a level of an anesthesia state and striatal dopamine concentration was investigated. The effect of halothane administration on dopamine level in rat striatal extracellular fluid was determined in tracheotomized rats, using an in vivo brain microdialysis method. The striatal dopamine was increased by halothane doses. The correlation coefficient between halothane and dopamine concentrations was 0.69.