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TREECON: a software package for the construction and drawing of evolutionary trees
1Departement Biochemie, Universiteit Antwerpen (UIA), Belgium.
Computer Applications in the Biosciences : CABIOS
|April 1, 1993
Summary
TREECON is a software package for creating and visualizing evolutionary trees. It includes programs for calculating sequence dissimilarities, constructing trees using various methods, rooting them, and drawing publication-quality figures.
Area of Science:
- Computational Biology
- Bioinformatics
- Evolutionary Biology
Background:
- Constructing and visualizing evolutionary trees is crucial for understanding biological relationships.
- Existing software may have limitations in flexibility or applicability across different data types.
Purpose of the Study:
- To develop a comprehensive software package, TREECON, for the construction and drawing of evolutionary trees.
- To provide versatile tools applicable to various dissimilarity matrices, including nucleic acid sequences.
Main Methods:
- The TREECON package comprises several modules: MATRIX for dissimilarity calculation and bootstrapping, TREE for tree construction, ROOT for rooting unrooted trees, and DRAW for visualization and editing.
- MATRIX is specialized for nucleic acid sequences, while TREE, ROOT, and DRAW are general-purpose.
Main Results:
- TREECON facilitates the entire process from data input to publication-ready evolutionary tree generation.
- The software supports multiple tree construction algorithms and allows for modifications in tree size and topology.
Conclusions:
- TREECON offers a flexible and user-friendly solution for phylogenetic analysis on IBM-compatible microcomputers.
- The package enhances the ability to visualize and interpret evolutionary relationships across diverse biological datasets.