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Related Experiment Videos

Acute acalculous cholecystitis

J C Hsu1, T L Yang, T C Wang

  • 1Department of Surgery, Mackay Memorial Hospital, Taipei, Taiwan, R.O.C.

Zhonghua Yi Xue Za Zhi = Chinese Medical Journal; Free China Ed
|April 1, 1993
PubMed
Summary
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Early detection of acute acalculous cholecystitis is crucial. Delayed treatment increases complication risks, including gallbladder perforation and mortality, highlighting the need for prompt surgical intervention.

Area of Science:

  • Gastroenterology
  • Surgical Pathology

Background:

  • Acute acalculous cholecystitis (AAC) is a severe gallbladder inflammation without gallstones.
  • Timely diagnosis and intervention are critical for managing AAC complications.

Purpose of the Study:

  • To emphasize the significance of early detection and diagnosis of AAC.
  • To evaluate the impact of treatment delay on patient outcomes in AAC.

Main Methods:

  • Retrospective analysis of 34 patients diagnosed with AAC.
  • Comparison of outcomes between patients treated within 48 hours versus those with delayed intervention (>48 hours).

Main Results:

  • A delay in surgery (>48 hours) was associated with a higher incidence of gallbladder perforation (5/20 patients).

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  • Patients treated within 48 hours did not experience perforation.
  • Overall mortality rate was 11% (4/34), with three deaths linked to delayed surgery and cardiovascular comorbidities.

    • Conclusions:

    • Prompt surgical intervention for AAC, ideally within 48 hours of symptom onset, significantly reduces the risk of gallbladder perforation.
    • Delayed treatment and comorbidities like cardiovascular disease are associated with increased mortality in AAC patients.