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Bacterial-induced activation of erythrocyte T-antigen complicating necrotising enterocolitis: a case report
R H Mupanemunda1, C F Kenyon, M J Inwood
1Department of Paediatrics, University of Western Ontario, London, Canada.
European Journal of Pediatrics
|April 1, 1993
Abstract:
Erythrocyte Thomsen-Friedenreich crypt antigen (T-antigen) activation is not an uncommon event in infants with severe necrotising enterocolitis (NEC). Transfusion of these infants with blood products containing plasma carries the risk of causing intravascular haemolysis. T-antigen activation is easily detected using a rapid simple lectin agglutination test. Early recognition of T-antigen activation ensures the correct choice of plasma free transfusion therapy. We describe an infant with severe NEC complicated by T-antigen activation and haemolysis.