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Angiosarcoma in the lung

A M Patel1, J H Ryu

  • 1Mayo Clinic, Division of Thoracic Diseases and Internal Medicine, Rochester, Minn 55905.

Chest
|May 1, 1993
PubMed
Summary
This summary is machine-generated.

Metastatic angiosarcoma to the lung is rare, often presenting with hemoptysis and multiple pulmonary nodules on chest radiographs. This aggressive cancer, frequently originating in the heart or breast, carries a poor prognosis with a median survival of nine months.

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Area of Science:

  • Oncology
  • Pulmonary Medicine
  • Radiology

Background:

  • Angiosarcoma involving the lung is a rare condition with poorly understood clinical features.
  • This study focuses on metastatic angiosarcoma to the lung, as primary lung angiosarcoma was not observed.

Purpose of the Study:

  • To characterize the clinical and radiographic findings of lung angiosarcoma.
  • To analyze a cohort of patients diagnosed with angiosarcoma metastatic to the lung.

Main Methods:

  • Retrospective analysis of 15 patients diagnosed with lung angiosarcoma between 1950 and 1990.
  • Review of clinical presentations, radiographic findings, primary tumor origins, and survival data.

Main Results:

  • Metastatic angiosarcoma to the lung was diagnosed antemortem in 12 of 15 cases.

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  • Common symptoms included hemoptysis (7/15), weight loss (6/15), cough (4/15), and chest pain (4/15).
  • Chest radiographs often showed multiple pulmonary nodules (11/15); common primary sites were heart and breast.

    • Conclusions:

    • Metastatic angiosarcoma to the lung presents with characteristic symptoms and radiographic findings.
    • The prognosis for angiosarcoma metastatic to the lung is poor, with a median survival of approximately nine months post-diagnosis.