Localization of the gene-encoding upstream stimulatory factor (USF) to human chromosome 1q22-q23

¹Department of Medicine, University of California, Los Angeles 90024.

|April 1, 1993

Abstract:

The upstream stimulatory factor, USF, is a ubiquitously expressed cellular transcription factor that binds to a symmetrical DNA sequence that is found in a variety of viral and cellular promoters. A full-length cDNA encoding the 43-kDa USF protein has previously been isolated. USF contains both helix-loop-helix and leucine repeats, which are involved in regulating its DNA binding and dimerization properties. We report the use of mouse-human somatic cell hybrids and in situ hybridization in localizing the gene-encoding USF to human chromosome 1q22-q23.

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Abstract:

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