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Selected white cell disorders

S Gin-Shaw1, G P Moore

  • 1Department of Emergency Medicine, Maricopa Medical Center, Phoenix, Arizona.

Emergency Medicine Clinics of North America
|May 1, 1993
PubMed
Summary
This summary is machine-generated.

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Emergency physicians often encounter abnormal white blood cell counts. This review covers the differential diagnosis of leukocytosis and leukopenia, and management strategies for neutropenic patients.

Area of Science:

  • Emergency Medicine
  • Hematology

Background:

  • Abnormal white blood cell (WBC) counts, including leukocytosis and leukopenia, are common in emergency department evaluations.
  • Leukocytosis has diverse causes, such as malignancy and infection.
  • Leukopenia is increasingly prevalent due to a growing immunocompromised patient population.

Purpose of the Study:

  • To review the differential diagnosis of leukocytosis and leukopenia.
  • To outline the management of neutropenic patients, with or without fever.
  • To provide current recommendations for empiric antibiotic regimens in neutropenic patients.

Main Methods:

  • Literature review of differential diagnoses for abnormal WBC counts.
  • Review of clinical guidelines and evidence for managing neutropenia.

Related Experiment Videos

  • Synthesis of current empiric antibiotic strategies.

    • Main Results:

    • Differential diagnosis for leukocytosis includes malignancy, infection, and other conditions.
    • Differential diagnosis for leukopenia involves various etiologies, particularly in immunocompromised hosts.
    • Management of neutropenia requires prompt assessment and appropriate antibiotic selection.

    Conclusions:

    • Accurate diagnosis of WBC count abnormalities is crucial for effective patient management.
    • Timely and evidence-based management of neutropenic patients can improve outcomes.
    • Understanding differential diagnoses and treatment guidelines is essential for emergency physicians.