Related Experiment Video
Updated: Aug 15, 2026

Targeting Gray Rami Communicantes in Selective Chemical Lumbar Sympathectomy
Published on: January 10, 2019
General anesthesia use in phenol intramuscular neurolysis in young children with spasticity
Insights
Intramuscular neurolysis effectively treated spasticity in children, with most patients requiring only an overnight hospital stay. This pediatric anesthesia approach minimized major complications during the elective procedures.
Area of Science:
- Pediatric Anesthesiology
- Neurology
- Surgical Procedures
Background:
- Spasticity in children presents significant challenges.
- Intramuscular neurolysis is a treatment option for pediatric spasticity.
- Anesthesia management is critical for pediatric neurolysis procedures.
Purpose of the Study:
- To review a nearly three-year experience with intramuscular neurolysis in children.
- To describe anesthetic agents and their effects in pediatric neurolysis.
- To evaluate the safety and efficacy of this anesthetic approach.
Main Methods:
- Review of 16 intramuscular neurolysis procedures in 13 children (aged 3-11 years).
- Detailed description of preoperative medications, induction, and maintenance anesthetic agents.
- Summary of principal and side effects of anesthetic agents.
Main Results:
- The study involved children with cerebral palsy, hydrocephalus, familial spastic paraplegia, and brain injury.
- A combination of anesthetic agents (chloral hydrate, atropine, pentothal, halothane, cyclopropane, nitrous oxide) was used.
- Most children had an overnight hospital stay; two required extended observation due to anesthetic side effects. No major complications occurred.
Conclusions:
- The described anesthetic regimen provides a light surgical plane for neurolysis.
- The operating room method with general anesthesia is safe for pediatric neurolysis.
- The presence of a pediatric anesthesiologist is a key reassuring factor.
Abstract:
This study reviews a nearly three-year experience of intramuscular neurolysis in children with spasticity. Thirteen children aged 3 to 11 years received general anesthesia during 16 procedures. Ten were cerebral palsy patients, one a congenital hydrocephalic, one a familial spastic paraplegic, and one a brain-injured child. Types of preoperative medications, induction and maintenance anesthetic agents are described, with indications for the particular choices of each type of drug. The principal and side effects of these agents during and after the 16 procedures are summarized. A combination of agents such as chloral hydrate; atropine if endotracheal intubation is necessary; pentothal, halothane, or cyclopropane for induction, and halothane-nitrous oxide for maintenance is our current choice of drugs to produce a light surgical plane of anesthesia. Advantages and disadvantages of the operating room method are considered. An overnight hospital stay was sufficient for all but two children, who required an additional evening of observation as the result of anesthetic side effects. No major complications were encountered in any of these elective procedures. The presence of a pediatric anesthesiologist during the procedure is perhaps to most reassuring aspect of the operating room-general anesthesia method.
More Related Videos
Related Concept Videos
Skeletal Muscle Relaxants: Therapeutic Uses
Local Anesthetics: Chemistry and Structure-Activity Relationship
Local Anesthetics: Clinical Application as Spinal Anesthesia
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Parenteral Anesthetics: Overview

