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Published on: January 18, 2018
Role of CT in chronic pulmonary embolism: comparison with pulmonary angiography
A A Tardivon1, D Musset, S Maitre
1Department of Radiology, Hôpital Antoine Béclère, Clamart, France.
Insights
Computed tomography (CT) offers advantages over pulmonary angiography for detecting proximal clots and analyzing distal pulmonary arteries in chronic pulmonary embolism (CPE). While less sensitive for stenosis, CT better characterizes pulmonary infarctions.
Area of Science:
- Radiology
- Pulmonary Medicine
- Medical Imaging
Background:
- Chronic pulmonary embolism (CPE) poses diagnostic challenges.
- Pulmonary angiography has been the gold standard but has limitations.
- Computed tomography (CT) is increasingly used for pulmonary vascular assessment.
Purpose of the Study:
- To evaluate the diagnostic value of CT compared to pulmonary angiography in patients with CPE.
- To assess the strengths and weaknesses of CT in visualizing thrombotic material and pulmonary vascular changes in CPE.
Main Methods:
- Retrospective review of CT scans and pulmonary angiograms from 21 consecutive patients with suspected CPE.
- Comparative analysis of CT and angiography findings regarding clot detection, vascular distortions, stenosis, and pulmonary infarctions.
Main Results:
- CT demonstrated superiority in identifying proximal clots, detecting three thrombi missed by angiography and ruling out three false positives.
- CT enabled analysis of pulmonary arteries beyond the 'amputations' seen in angiography.
- CT was less sensitive than angiography for vascular distortions (38% vs. 50%) and stenosis (35% vs. 71.8%).
- CT provided better detection and characterization of pulmonary infarctions.
- High-resolution CT improved delineation of parenchymal ground-glass opacities, observed in 18 patients.
Conclusions:
- CT serves as a valuable adjunct to pulmonary angiography in the comprehensive assessment of chronic pulmonary embolism.
- CT's ability to detect proximal clots and analyze distal vessels, along with superior infarction characterization, enhances diagnostic accuracy in CPE.
Abstract:
To assess the value of CT in chronic pulmonary embolism (CPE), CT scans and pulmonary angiograms of 21 consecutive patients were reviewed. Computed tomography was better than angiography in assessing proximal clots (three thrombi not seen by angiography, three angiographic false-positives confirmed by surgery). Furthermore, CT was able to analyze pulmonary arteries distal to angiographic amputations. Computed tomography was less sensitive than angiography for vascular distortions (38 vs. 50%) and stenosis (35 vs. 71.8%). Pulmonary infarctions were better detected and characterized by CT than by angiography. Isolated parenchymal ground-glass opacities were seen by CT in 18 patients, especially in those with right cardiomegaly. High resolution CT delineated them better than did standard CT. Computed tomography may be a useful adjunct to angiography in the assessment of CPE.
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