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Updated: Aug 10, 2026

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer
Published on: July 6, 2017
[Surface microscopic patterns of an experimental model of surgically induced carcinogenesis]
J Castejón Casado1, C Jimenez Alvarez, P V Crespo Ferrer
1Servicio de Cirugía Pediátrica H.G.E. Virgen de las Nieves, Granada.
Abstract:
An experimental model of carcinogenesis is developed by authors, using internal urinary diversion in Wistar rats. Results show the transformation of normal digestive pattern, discovering proliferative-inflammatory changes at the first time which after go to an histiotypical tumorous pattern. They conclude at the carcinogenicity of the presented surgical model and is described the evolution of the superficial morphological pattern during the tumorigenic process.
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