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Giant cell fibroblastoma

R Nair1, S V Kane, A Borges

  • 1Department of Medical Oncology, Tata Memorial Hospital, Bombay, India.

Journal of Surgical Oncology
|June 1, 1993
PubMed
Summary
This summary is machine-generated.

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Giant cell fibroblastoma, a rare pediatric neoplasm, presents as a mix of spindle and giant cells. Wide surgical excision is the recommended treatment, with no need for chemotherapy.

Area of Science:

  • Pediatric oncology
  • Dermatopathology
  • Surgical pathology

Background:

  • Giant cell fibroblastoma is a rare soft tissue neoplasm.
  • This report details a case in a 1 1/2-year-old male child.
  • Literature review on giant cell fibroblastoma is presented.

Observation:

  • The tumor exhibited a characteristic mixture of spindle cells and multinucleated giant cells.
  • A myxoid or collagenous background was noted in the tumor's stroma.
  • Pathological findings were consistent with a diagnosis of giant cell fibroblastoma.

Findings:

  • The clinical course and pathological features suggest classification with pediatric fibromatoses.
  • Complete removal of the tumor via wide excision was curative.

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  • No adjuvant chemotherapy was required for this case.

    • Implications:

    • Giant cell fibroblastoma should be considered in the differential diagnosis of pediatric soft tissue tumors.
    • Wide surgical excision is the primary and sufficient treatment modality.
    • This finding supports conservative management without chemotherapy for localized disease.