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Cow's milk, diabetes, and infant feeding
1Department of Nutrition, University of Massachusetts, Amherst 01003.
Nutrition Reviews
|March 1, 1993
Summary
A recent study links cow's milk antibodies to insulin-dependent diabetes mellitus (IDDM). This finding reignites debate on using cow's milk in infant nutrition, impacting infant feeding recommendations.
Area of Science:
- Immunology
- Endocrinology
- Pediatrics
Background:
- Recent research suggests a correlation between elevated serum antibodies to cow's milk protein and the development of insulin-dependent diabetes mellitus (IDDM).
- This association has prompted renewed discussion about the safety and appropriateness of cow's milk-based formulas in infant diets.
Purpose of the Study:
- To investigate the potential link between antibodies to cow's milk protein and the incidence of insulin-dependent diabetes mellitus.
- To evaluate the implications of this link on current infant feeding practices and recommendations.
Main Methods:
- Serum samples were analyzed for the presence and levels of antibodies targeting specific cow's milk proteins.
- Patient data, including diagnosis of insulin-dependent diabetes mellitus, were reviewed and correlated with antibody levels.
Main Results:
- A statistically significant association was observed between higher serum levels of antibodies to cow's milk protein and the onset of insulin-dependent diabetes mellitus.
- The findings suggest a potential role for immune responses to cow's milk protein in the pathogenesis of IDDM.
Conclusions:
- The study provides evidence supporting a connection between cow's milk protein sensitization and insulin-dependent diabetes mellitus.
- Further research is warranted to elucidate the mechanisms involved and to inform guidelines on infant nutrition and diabetes prevention.