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Cholesterol 7 alpha hydroxylase promoter separated from cyclophilin pseudogene by Alu sequence
J F Thompson1, M E Lira, D B Lloyd
1Molecular Genetics and Protein Chemistry Research Department, Pfizer Inc., Groton, CT 06340.
Biochimica Et Biophysica Acta
|June 12, 1993
Abstract:
The promoter for human cholesterol 7-alpha hydroxylase has been cloned and sequenced. In the regions previously described, our sequence agrees well with one report but not with another. At position -469, we find a widespread MaeII polymorphism. At -2636, there is an Alu sequence flanked by runs of adenines. Upstream of the Alu sequence, there is a cyclophilin pseudogene oriented in the opposite direction.