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Medications and the older driver

W A Ray1, P B Thapa, R I Shorr

  • 1Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.

Clinics in Geriatric Medicine
|May 1, 1993
PubMed
Summary
This summary is machine-generated.

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Many common medications, especially benzodiazepines, impair older drivers

Area of Science:

  • Geriatric Medicine
  • Pharmacology
  • Traffic Safety

Background:

  • Older drivers are frequent medication users, necessitating an understanding of drug effects on driving.
  • Existing evidence indicates that several commonly prescribed medications can negatively impact driving safety in the elderly population.

Purpose of the Study:

  • To review and summarize evidence on how specific medications affect the safety of older drivers.
  • To inform prescribing practices and highlight areas for future research in geriatric pharmacotherapy and driving.

Main Methods:

  • Review of evidence, including psychomotor function data and epidemiological studies on crash involvement and injuries.
  • Analysis of data related to benzodiazepines, cyclic antidepressants, hypoglycemics, and other sedating drugs.

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Main Results:

  • Benzodiazepines, particularly high doses and long half-life compounds, show consistent evidence of psychomotor impairment and adverse driving safety effects.
  • Cyclic antidepressants may adversely affect driving safety, with a need for more research, especially concerning depression's impact.
  • Hypoglycemics present a basis for concern regarding driving impairment, though questions remain.

Conclusions:

  • Cautious prescribing of medications, especially benzodiazepines and certain antidepressants, is crucial for older drivers.
  • Non-pharmacologic alternatives and careful dose/duration management are recommended.
  • Further research is needed to fully understand drug-disease-patient interactions affecting driving safety in the elderly.