A study of enzymohistochemistry of cerebral cortical injury

Morphologic changes and quantitative determination by enzymohistochemistry were studied during various survival times after cortical injury in 60 rats. It was found that acid phosphatase (ACP) showed regular changes with various survival times after cortical injury. The ACP content decreased from 30 min to 6 h, and began to increase after 6 h; the ACP content in the region around injury decreased over the period of 5 days to 3 weeks after; the ACP content in the injured region (region around injury and control region of injury) decreased in a linear fashion with the time. The linear correlation was very marked; one may accurately estimate the survival time with injury by the regression equation given.