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Clinical usefulness of continuous administration of Nocardia rubra cell wall skeleton (N-CWS) in diffuse
S Ishioka1, S Hozawa, K Hasegawa
1Second Department of Internal Medicine, Hiroshima University School of Medicine, Japan.
Biotherapy (Dordrecht, Netherlands)
|January 1, 1993
Abstract:
Eight patients with diffuse panbronchiolitis (DPB) who had repeated intractable airway infections were continuously treated with Nocardia rubra cell wall skeleton (N-CWS), a biological response modifier. As a result, subjective symptoms were reduced in 6 patients. Antibiotics therapy could be discontinued completely in two patients and the dose of antibiotics could be reduced considerably in two other patients. No adverse reactions in relation to N-CWS were observed. These results suggest that N-CWS is effective in treating erythromycin-resistant DPB.