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Angiotensin-converting enzyme inhibitor fetopathy
P G Pryde1, A B Sedman, C E Nugent
1Department of Obstetrics/Gynecology, University of Michigan Medical Center, Ann Arbor.
Journal of the American Society of Nephrology : JASN
|March 1, 1993
Summary
Angiotensin-converting enzyme (ACE) inhibitors pose significant risks during pregnancy, potentially causing severe fetal harm. Due to fetotoxic effects, these hypertension drugs are not recommended for pregnant women, especially in later trimesters.
Area of Science:
- Pharmacology
- Teratology
- Obstetrics
Background:
- Angiotensin-converting enzyme (ACE) inhibitors are common antihypertensive medications.
- Pregnancy introduces specific risks when using ACE inhibitors due to potential fetal effects.