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Carbamazepine, serum thyroid hormones and myocardial function in epileptic patients
J I Isojärvi1, K E Airaksinen, M Repo
1Department of Neurology, University of Oulu, Finland.
Journal of Neurology, Neurosurgery, and Psychiatry
|June 1, 1993
Abstract:
Serum thyroid hormone and thyrotropin levels were assayed and the myocardial function was evaluated by measuring systolic time intervals both in 30 patients with epilepsy on long-term carbamazepine monotherapy and in 19 healthy volunteers. Serum thyroxine, free thyroxine and triiodothyronine levels were significantly lower (p < 0.001) in the patient group than in the control group and systolic time intervals were similar in both groups.