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Intraluminal fungal colonization of gastrostomy tubes
K Gottlieb1, J Leya, D M Kruss
1Edward Hines, Jr., Veterans Affairs Hospital, Section of Gastroenterology, Hines, Illinois 60141.
Abstract:
Percutaneous endoscopic gastrostomy tubes are frequently colonized with fungal and bacterial organisms. This has not been previously reported. In our sample of 10 patients, nine percutaneous endoscopic gastrostomy tubes were colonized with fungi. This occurred as early as 1 week after placement. Candida tropicalis was isolated in five patients. It is hypothesized that a variety of fungi use components of the gastrostomy tube polymer, such as polymer additives, which contribute to the structural deterioration of the tube.
Insights
Fungal colonization of percutaneous endoscopic gastrostomy tubes is common, with Candida tropicalis frequently identified. This microbial overgrowth may impact tube integrity and patient health.
Area of Science:
- Microbiology
- Gastroenterology
- Medical Device Science
Background:
- Percutaneous endoscopic gastrostomy (PEG) tubes are essential medical devices for nutritional support.
- Colonization of PEG tubes by microorganisms is a known complication.
- Fungal colonization of PEG tubes has not been previously reported.
Purpose of the Study:
- To investigate the prevalence of fungal and bacterial colonization in PEG tubes.
- To identify the specific fungal species colonizing PEG tubes.
- To explore potential mechanisms linking fungal colonization to tube deterioration.
Main Methods:
- Sample collection from 10 patients with PEG tubes.
- Microbiological analysis to identify fungal and bacterial organisms.
- Fungal species identification, with a focus on Candida species.
Main Results:
- Nine out of 10 PEG tubes showed fungal colonization.
- Fungal colonization was observed as early as 1 week post-placement.
- Candida tropicalis was the most frequently isolated fungal species (in 5 patients).
Conclusions:
- Fungal colonization of PEG tubes is a frequent occurrence.
- Candida tropicalis is a predominant colonizer.
- Fungi may utilize PEG tube polymer components, potentially leading to structural degradation.
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