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The Y-specific p21A1/TaqI polymorphism occurs in four major population Oroups
1MRC Human Ecogenetics Research Unit, Department of Human Genetics, School of Pathology, South African Institute for Medical Research, Johannesburg.
Human Heredity
|January 1, 1993
Abstract:
The p21A1/TaqI polymorphism was studied in 904 individuals in 23 African population groups, encompassing the Caucasoid, Negroid, Khoisan and Pygmy populations. The frequency of the polymorphism was higher than previously reported, with the rarer allele occurring at frequencies ranging up to 0.41. No distinct trends in population frequency were observed, suggesting that the polymorphism is of little value in anthropological population studies. The existence of several TaqI mutations, in both time and position within the repeat unit, is indicated.