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In vitro susceptibility of Streptococcus mutans to chlorhexidine and six other antimicrobial agents
H Järvinen1, J Tenovuo, P Huovinen
1Antimicrobial Research Laboratory, National Public Health Institute, Turku, Finland.
Antimicrobial Agents and Chemotherapy
|May 1, 1993
Abstract:
The susceptibility of Streptococcus mutans to chlorhexidine and to six commonly used, systemic antibacterial agents (amoxicillin, cefuroxime, penicillin, sulfamethoxazole-trimethoprim, tetracycline, and erythromycin) was studied for 424 clinical isolates from 116 children and students. The MIC of chlorhexidine for all isolates was < or = 1 micrograms/ml. No resistance to the other antimicrobial agents was detected. Although widely exposed to various antimicrobial agents, S. mutans has remained susceptible to common antimicrobial agents, most importantly to chlorhexidine.