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Ankylosing spondylitis

I Haslock1

  • 1University of Durham, South Cleveland Hospital, Middlesbrough, UK.

Bailliere'S Clinical Rheumatology
|February 1, 1993
PubMed
Summary
This summary is machine-generated.

Ankylosing spondylitis (AS) can affect the respiratory system, causing chest pain and reduced movement. While lung complications are rare, they can be severe, necessitating prompt treatment.

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Area of Science:

  • Rheumatology
  • Pulmonology
  • Physical Therapy

Background:

  • Ankylosing spondylitis (AS) is a chronic inflammatory condition primarily affecting the spine and sacroiliac joints.
  • AS can lead to respiratory complications due to inflammation and calcification of the chest wall and spine.
  • While diaphragmatic function is typically preserved, chest wall rigidity can impair respiratory mechanics.

Purpose of the Study:

  • To review the respiratory manifestations of ankylosing spondylitis.
  • To discuss the impact of AS on chest wall mechanics and lung function.
  • To outline current treatment strategies for respiratory involvement in AS.

Main Methods:

  • Literature review of studies on respiratory complications in ankylosing spondylitis.

Related Experiment Videos

  • Analysis of the pathophysiology of chest wall and lung involvement in AS.
  • Synthesis of information on diagnostic and therapeutic approaches.

    • Main Results:

    • Chest wall pain, reduced chest expansion, and dorsal stoop are common respiratory manifestations.
    • Minor restrictive changes in lung function are typical, often compensated by diaphragmatic breathing.
    • Apical fibrobullous lung disease occurs in a small subset of AS patients, with potential for severe complications like aspergillosis.
    • Cardiac involvement is the most frequent cause of dyspnea in AS patients.

    Conclusions:

    • Respiratory involvement in AS, though often mild, requires careful monitoring.
    • Management focuses on physiotherapy, symptom management, and treating pulmonary complications like superinfections.
    • Early diagnosis and management of cardiac and pulmonary issues are crucial for improving outcomes in AS patients.