Related Experiment Video
Updated: Aug 19, 2026

Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol
Published on: July 28, 2018
Mediastinal widening--a valuable radiographic sign of superior vena cava thrombosis
1Department of Radiology, Royal Marsden Hospital, Sutton, Surrey.
Insights
Mediastinal widening on chest X-rays is a key indicator of superior vena cava (SVC) thrombosis in patients with Hickman catheters. Recognizing this sign aids in earlier diagnosis and treatment of catheter-related SVC obstruction.
Area of Science:
- Radiology
- Vascular Surgery
- Oncology
Background:
- Indwelling intravenous catheters, such as Hickman catheters, are increasingly associated with superior vena cava (SVC) thrombosis.
- SVC thrombosis can lead to benign SVC obstruction, a condition requiring prompt recognition.
Purpose of the Study:
- To evaluate the radiographic findings of SVC thrombosis in patients with Hickman catheter insertion.
- To determine the utility of mediastinal widening as an early diagnostic sign of SVC thrombosis.
Main Methods:
- Retrospective review of PA chest radiographs from nine patients with SVC thrombosis secondary to Hickman catheter placement.
- Analysis of radiographic signs, including mediastinal widening and catheter displacement, in relation to symptom onset.
Main Results:
- All nine patients exhibited mediastinal widening concurrent with SVC thrombosis.
- Four patients showed radiographic signs of SVC thrombosis before symptom manifestation.
- Lateral displacement of the Hickman catheter was observed in five patients.
Conclusions:
- Superior mediastinal widening is a significant radiographic marker for SVC thrombosis in patients with Hickman catheters.
- Early detection of mediastinal widening can facilitate earlier diagnosis and intervention for SVC thrombosis.
Abstract:
Thrombosis due to indwelling intravenous catheters has become increasingly recognized as an important cause of the benign superior vena cava (SVC) obstruction. We evaluated the PA chest radiographs of nine patients with SVC thrombosis related to Hickman catheter insertion. All nine patients showed mediastinal widening at the time of developing SVC thrombosis and four patients had radiographic signs before the onset of symptoms. Five patients demonstrated lateral displacement of the Hickman catheter with the development of SVC thrombosis. The development of superior mediastinal widening is a valuable sign of SVC thrombosis and its recognition may allow earlier diagnosis and treatment of this condition.
Related Concept Videos
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Mitral Stenosis II: Clinical features and Diagnostic Tests
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

