[Chronic intermittent peritoneal dialysis: a 12-year experience]

Area of Science:

• Nephrology
• Renal Medicine
• Dialysis Therapy

Background:

• Chronic renal failure (CRF) necessitates renal replacement therapy.
• Peritoneal dialysis offers an alternative to hemodialysis.
• The efficacy and safety of intermittent peritoneal dialysis (IPD) in a mixed adult population, including diabetics, require evaluation.

Purpose of the Study:

• To assess the outcomes of intermittent peritoneal dialysis (IPD) in adult patients with chronic renal failure.
• To compare the results between diabetic and non-diabetic patients undergoing IPD.
• To evaluate the incidence of complications such as peritonitis and exit site infections.

Main Methods:

• A retrospective analysis of 46 adult patients treated with IPD since 1981.
• Patients received 2 dialysis sessions per week with specified exchange volumes and dwell times.
• Data collected included patient demographics, dialysis parameters, complication rates, and survival outcomes.

Main Results:

• Satisfactory arterial pressure control was achieved.
• Diabetic patients exhibited lower serum calcium, alkaline phosphatases, and parathyroid hormone (PTH) levels.
• The incidence of peritonitis was 1 episode/14 months/patient, with Staphylococcus aureus as the primary pathogen (47%).
• Exit site infection occurred at 1 episode/34 months/patient, predominantly caused by Staphylococcus aureus (83%).
• Actuarial survival at 12 and 24 months was 89% and 67%, respectively, with no significant difference between diabetic and non-diabetic groups.
• Common reasons for treatment discontinuation included transfer to hemodialysis (52%) and death (23%).

Conclusions:

• Intermittent peritoneal dialysis is a viable and effective treatment option for chronic renal failure.
• IPD demonstrates comparable survival outcomes for both diabetic and non-diabetic patients.
• The study supports IPD as a suitable alternative renal replacement therapy, even for patients with diabetes.