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[Varicella-zoster virus pancreatitis in hematologic diseases]
M Pulik1, F Teillet, F Teillet-Thiebaud
1Service d'Hématologie, Hôpital Victor-Dupouy, Argenteuil
Annales De Medecine Interne
|January 1, 1995
Summary
Varicella-zoster pancreatitis is a rare complication in immunocompromised patients, often presenting with abdominal pain before a rash. Early antiviral therapy is crucial for managing this severe infection.
Area of Science:
- Infectious Diseases
- Gastroenterology
- Immunology
Context:
- Reports four cases of varicella-zoster pancreatitis in immunocompromised patients.
- Highlights severe immunodeficiency due to chronic lymphoproliferative disorders and immunosuppressive therapy.
- Notes that varicella-zoster pancreatitis is an unusual manifestation of varicella-zoster virus infection.
Purpose:
- To describe the clinical presentation and outcomes of varicella-zoster pancreatitis.
- To emphasize the importance of early diagnosis and treatment in at-risk populations.
- To raise physician awareness of this rare but serious condition.
Summary:
- Patients presented with acute epigastric pain and elevated amylase, preceding a vesicular rash by approximately 8 days.
- The study underscores that abdominal pain can be the initial symptom, even without a rash.
- Early antiviral treatment is recommended for suspected cases in immunocompromised individuals.
Impact:
- Suggests a diagnostic approach for varicella-zoster pancreatitis in immunocompromised hosts.
- Emphasizes the need for prompt antiviral intervention to improve patient outcomes.
- Contributes to understanding rare complications of varicella-zoster virus in vulnerable populations.
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