[Morphologic heterogeneity of adrenal cortical adenoma]

45 adrenal cortex adenomas were examined for morphological atypia after adrenalectomy. The majority of clear-, dark- and mixed cell adenomas are characterized by tissue atypia in the form of alveolar-trabecular structure. Adenoma heterogeneity is manifested by cellular polymorphism of a poor, moderate and high degree. It is suggested to distinguish adenomas formed of large, giant and multinuclear cells from dark cell adenomas and to consider them as a special independent giant cell variant.