[Histopathological analysis of A-P shunt in peripheral intrahepatic cholangiocarcinoma]

A-P shunts observed in peripheral intrahepatic cholangiocarcinoma were analyzed histopathologically. The study group consisted of 30 patients who underwent angiography at Saitama Medical School between February 1980 and July 1992. Histopathological analysis was done from biopsy, surgery and/or autopsy specimen. The male to female ratio was 7 to 8, and the mean age of the subjects was 61.3 years. All cases were adenocarcinoma and the histological grade was poorly differentiated in 43.3%, moderate in 23.3% and well differentiated in 33.3%. A-P shunt was observed clearly in 2 patients (6.7%), one was poorly differentiated and the other was moderate. Histological study showed dominant tumor invasion into hepatic lobules, and hepatic arterial and portal vein branches, excessive fibrous tissue within and around the tumor and Glisson's sheath. Is there more?