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[Tissue levels of some elements in hyperthyreosis in rabbits]
K Pasternak1, S Szymonik-Lesiuk, B Floriańczyk
1Katedra i Zaklad Chemii Fizjologicznej, Akademia Medyczna w Lublinie.
Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina
|January 1, 1993
Summary
Hyperthyroidism significantly increases copper, zinc, magnesium, and calcium levels in most tissues. Exceptions include higher zinc and copper in liver and heart, and copper in kidney during normal thyroid function.
Area of Science:
- Biochemistry and Physiology
- Trace Element Metabolism
- Endocrinology
Context:
- Investigating the impact of experimentally induced hyperthyroidism on mineral concentrations.
- Analyzing elemental distribution across vital organs and muscle tissue.
Purpose:
- To quantify the concentrations of Copper (Cu), Zinc (Zn), Magnesium (Mg), and Calcium (Ca).
- To compare elemental levels in brain, heart, lung, liver, kidney, and femoral muscles between hyperthyroid and euthyroid states.
Summary:
- Hyperthyroidism generally elevates Cu, Zn, Mg, and Ca concentrations across studied tissues.
- Specific exceptions noted: higher Zn and Cu in liver/heart, and Cu in kidney tissues during euthyroidism.
Impact:
- Provides insights into altered mineral homeostasis during hyperthyroidism.
- Highlights tissue-specific elemental responses to thyroid hormone imbalance.
- Contributes to understanding the physiological effects of hyperthyroidism on trace elements.