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Excimer laser lamellar keratoplasty
D B Cano1, N A Downie, I M Young
1University of Melbourne Department of Ophthalmology, Australia.
Australian and New Zealand Journal of Ophthalmology
|August 1, 1995
Summary
Excimer laser lamellar keratoplasty shows promise for treating deep corneal scars. This technique appears safe for the corneal endothelium and host bed preparation.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Laser Technology
Background:
- Deep corneal scars in the central optical zone can impair vision.
- Lamellar keratoplasty is a surgical option for corneal opacity.
- Excimer laser technology offers precision in tissue ablation.
Purpose of the Study:
- To evaluate the efficacy and safety of excimer laser-assisted lamellar keratoplasty for deep corneal scars.
- To assess the smoothness of the host bed and donor button prepared by the excimer laser.
- To determine the impact of excimer laser ablation on graft-host interface opacity and endothelial cells.
Main Methods:
- Excimer laser lamellar keratoplasty was performed on 19 rabbits.
- Animals were observed for 9 to 12 weeks post-surgery.
- Scanning electron microscopy was used to examine the endothelial surface.
Main Results:
- Minimal opacity was observed at the graft-host interface.
- Scanning electron microscopy revealed no significant differences in the endothelial surface between treated and untreated eyes.
- The excimer laser effectively prepared smooth surfaces for both the host bed and donor button.
Conclusions:
- Excimer laser lamellar keratoplasty is a feasible technique for treating deep corneal scars in eyes with normal endothelium.
- Further research is needed to compare its outcomes with conventional lamellar dissection methods.